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Vitamin K
Indications
Prophylaxis and treatment haemorrhagic disease of the newborn (since vitamin K from the mother may possibly be insufficient due to its poor passage through the placenta and because intestinal bacteria responsible for its natural synthesis are not present for 1st 5-8 days after birth); in the management of overdose of anti-coagulants; in patients with fat mal-absorption (Vitamin K is fat soluble hence it is not absorbed in fat mal-absorption disorders); treatment and prophylaxis of various coagulation disorders due to impaired synthesis of factors II, VII, IX, and X (this may result from vitamin K deficiency, impaired activity of vitamin K eg. hypoprothrombinemia due to coumarin or indanedione-derived oral anticoagulants and other drugs.
Dose/Application
Should be based on laboratory tests of clotting functions. See under product below. Dose 2.5 to 10mg, or up to 25mg. When minor bleeding progresses to major bleeding, administer 5-25 mg [up to 50mg] parenteral vitamin K1. In emergency situations of severe haemorrhage, 200-500 mL of whole blood or fresh frozen plasma or commercial Factor IX complex can be administered.
Mode of action
Precautions
Contraindications
Side Effects
Pregnancy risk
Special information
Brands containing this Ingredient
Name Form. Strength Pack Price Insert Manufacturer Distributor
Mediphyto inj 2mg/mL 1 KES60.00
Konakion, phytomenadione inj 10mg/mL 10 KES900.00
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