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Zoledronic acid
Indications
Prevention of skeletal related events (pathological fractures, spinal compression, radiation or surgery to bone, or tumor-induced hypercalcemia) in patients w/ advanced malignancies involving bone; Treatment of hypercalcemia of malignancy
Dose/Application
Prevention of skeletal related events (pathological fractures, spinal compression, radiation or surgery to bone, or tumor-induced hypercalcemia) in patients w/ advanced malignancies involving bone Recommended dose: 4 mg (diluted with 100ml NaCl 0.9% w/v or glucose 5% w/v soln) given as a 15-min IV infusion every 3-4 wk. Reduce dose in patients with preexisting mild to moderate renal impairment. Treatment of hypercalcemia of malignancy (HCM: Recommended dose- 4 mg given as a single 15-min IV infusion. No dose adjustment in patients with mild to moderate renal impairment. Without hypercalcemia 500 mg oral Ca supplement and 400 iu vitamin D daily.
Mode of action
Precautions
Contraindications
Side Effects
Pregnancy risk
Special information
Brands containing this Ingredient
Name Form. Strength Pack Price Insert Manufacturer Distributor
Zolrex Inj 4mg 1 KES3,750.00
Zoledro.Denk. inj 4mg/5mL 1 KES11,709.00
Zometa. inj 4mg/vial 1 KES24,609.83
Amnol. inj. 4mg 1 KES4500.00
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